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Is There Still a GLP-1 Shortage? FDA's Database on 2 November 2026: Liraglutide Yes, Semaglutide and Tirzepatide No

FDA's drug-shortage records, read 2 November 2026: liraglutide (Victoza, Saxenda and generics) has been listed since 18 July 2023, with Victoza and Saxenda at 'limited availability'. Semaglutide injection and tirzepatide have no shortage entry; FDA declared those shortages resolved on 21 February 2025 and 19 December 2024. Three Rybelsus strengths are marked to be discontinued.

Ronald R · Edited by Caroline S · Published 2026-11-02

Illustration: An empty, clear pharmaceutical vial on a white plate next to a piece of wood on a kitchen counter.
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There is no national shortage of Ozempic, Wegovy, Mounjaro or Zepbound in FDA's records. The one GLP-1 molecule still listed is liraglutide, the older daily drug sold as Victoza and Saxenda, which has been on FDA's list since July 2023. The semaglutide and tirzepatide shortages that drove the compounding boom were declared over in December 2024 and February 2025.

This page reads FDA's drug-shortage data through its public openFDA interface on 2 November 2026 (dataset last updated 30 October 2026), and FDA's own statement on how the resolved shortages ended. It is a dated register. A shortage entry is about national supply; it says nothing about whether one pharmacy has a pen in stock today.

The register on 2 November 2026

Molecule (brands) Records in FDA's shortage data Status What the records say
Liraglutide (Victoza, Saxenda, generics) 11 9 Current · 2 To Be Discontinued first posted 18 July 2023; Victoza and Saxenda "Limited Availability"; six generic packs "Available"
Semaglutide injection (Ozempic, Wegovy) 0 — shortage resolved 21 February 2025
Semaglutide tablets (Rybelsus) 3 To Be Discontinued 3, 7 and 14 mg, dated 4 June 2026; to be replaced by Ozempic tablets
Tirzepatide (Mounjaro, Zepbound) 0 — shortage resolved 19 December 2024
Dulaglutide (Trulicity) 0 — no record
Exenatide 0 — no record

Source: openFDA drug shortages endpoint, queried by generic name. openFDA states its data are "unvalidated" and should not be relied on for medical decisions; FDA's own Drug Shortages database is the authoritative listing.

Liraglutide, pack by pack

Every liraglutide pack in the data is the same strength, 6 mg/mL in a 3 mL pen. What differs is the label it is sold under and its supply status:

Pack Company Status Availability Reason or note Last updated
Victoza (NDC 0169-4060-12) Novo Nordisk Current Limited "Delay in shipping of the drug"; duration "TBD" 22 Sep 2026
Victoza (NDC 0169-4060-13) Novo Nordisk Current Limited same 22 Sep 2026
Saxenda (NDC 0169-2800-15) Novo Nordisk Current Limited manufacture discontinued; available "until discontinuation in January 2027" 22 Sep 2026
Saxenda (same NDC) Novo Nordisk To Be Discontinued — posted 25 Aug 2026 25 Aug 2026
Liraglutide (NDC 0480-3667-20, -22) Novo Nordisk, "Distributed by Teva" Current Available — 22 Sep 2026
Liraglutide (NDC 0143-9144-02, -03) Hikma Current Available — 14 Oct 2026
Liraglutide (NDC 71288-563-84, -85) Meitheal Current Available — 27 Aug 2026
Liraglutide (NDC 0480-7250-46) Teva To Be Discontinued — manufacture discontinued, posted 14 May 2026 14 May 2026

The pattern is that the brand packs are the scarce ones. The generic packs are listed as available while staying under the same 2023 shortage entry. Which generics substitute for Victoza and which for Saxenda is a separate question, answered by FDA's equivalence codes on the Saxenda and Victoza pages. An "Available" generic is not automatically a substitute for both brands.

How the semaglutide and tirzepatide shortages ended

FDA's page on compounding as supply stabilised (content current as of 1 April 2026) gives both timelines. Both shortages began in 2022, "due to increased demand".

Tirzepatide Semaglutide
Shortage declared resolved 19 December 2024 (reaffirming a 2 October 2024 decision after re-evaluation) 21 February 2025
Enforcement discretion ended, 503A state-licensed pharmacies 18 February 2025 (held pending litigation; ended after a court denied a preliminary injunction on 5 March 2025) 22 April 2025 (held pending litigation; ended after a court denied a preliminary injunction on 24 April 2025)
Enforcement discretion ended, 503B outsourcing facilities 19 March 2025 22 May 2025

Why those dates still matter. While a drug is on FDA's shortage list, compounders may make copies of it under rules that otherwise forbid "essentially copies" of an approved drug. The end of the shortage closed that route. What compounding is still sold, and on what legal footing, is on compounded semaglutide and compounded tirzepatide vs Zepbound.

Two discontinuations that are not shortages

  • Rybelsus 3, 7 and 14 mg. FDA's data list all three as "To Be Discontinued", posted 4 June 2026, with the note: "These products will be replaced by Ozempic (semaglutide) tablets." The Rybelsus label reports "no clinically significant differences" in steady-state exposure between 3, 7 and 14 mg of Rybelsus and 1.5, 4 and 9 mg of Ozempic tablets in healthy subjects, and states that the two "are not substitutable on a mg-to-mg basis". The oral products are compared on the Ozempic pill.
  • Saxenda. Novo Nordisk has notified FDA that the pack will be discontinued, available "until discontinuation in January 2027". Generic liraglutide rated equivalent to Saxenda exists; see Saxenda vs Zepbound and the Saxenda page.

A discontinuation entry means the maker has told FDA it will stop making that product. It is not a statement that the molecule will be unavailable.

What the register cannot tell anyone

  • Local stock. A pharmacy can be out of one strength on one day without any national shortage. FDA's list tracks national supply.
  • Insurance or price. A drug that is not in shortage can still be unaffordable or not covered; those questions are on GLP-1 cost and how to get a GLP-1.
  • Future shortages. The records show the present and the past. They do not forecast supply.

Sources

  • openFDA drug shortages endpoint, queried 2 November 2026 for semaglutide, tirzepatide, liraglutide, dulaglutide and exenatide (dataset last updated 30 October 2026).
  • FDA, "FDA clarifies policies for compounders as national GLP-1 supply begins to stabilize", content current as of 1 April 2026, read 2 November 2026: fda.gov.
  • Rybelsus and Ozempic tablets US prescribing information (effective 30 January 2026), sections 2.1 and 12.3, read on DailyMed 2 November 2026.

Frequently asked questions

Is there still a shortage of Ozempic or Wegovy?

Not in FDA's records. On 2 November 2026 semaglutide injection had no entry in FDA's shortage data. FDA declared the semaglutide shortage resolved on 21 February 2025. Local pharmacies can still be out of a particular strength on a particular day; that is a stock question, not a national shortage.

Is there a shortage of Zepbound or Mounjaro?

No. Tirzepatide had no shortage record on 2 November 2026. FDA declared its shortage resolved on 19 December 2024, in an order that replaced its 2 October 2024 decision.

Which GLP-1 is still in shortage?

Liraglutide. Its records, first posted on 18 July 2023, were still 'Current' on 2 November 2026: Victoza and Saxenda at limited availability, and six generic liraglutide packs listed as available.

Can pharmacies still compound semaglutide or tirzepatide because of the shortage?

FDA's shortage-based enforcement discretion has ended for both: for tirzepatide on 18 February 2025 (state pharmacies) and 19 March 2025 (outsourcing facilities), for semaglutide on 22 April 2025 and 22 May 2025. What compounding remains lawful outside the shortage rules is set out on this site's compounded-semaglutide page.

Is Rybelsus being discontinued?

FDA's shortage data lists the 3, 7 and 14 mg Rybelsus tablets as 'To Be Discontinued' from 4 June 2026, noting they will be replaced by Ozempic tablets (semaglutide 1.5, 4 and 9 mg). The two tablets are not interchangeable milligram for milligram; any change is made by the prescriber.